Cargando…

Robust anti‐nociceptive effects of monoacylglycerol lipase inhibition in a model of osteoarthritis pain

BACKGROUND AND PURPOSE: Chronic pain is often a symptom of knee osteoarthritis (OA) for which current analgesics are either inadequate or are associated with serious side effects. The endocannabinoid system may offer alternative targets for pain relief. We evaluated the effects of a potent and selec...

Descripción completa

Detalles Bibliográficos
Autores principales: Burston, James J, Mapp, Paul I, Sarmad, Sarir, Barrett, David A, Niphakis, Micah J, Cravatt, Benjamin F, Walsh, David A, Chapman, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056226/
https://www.ncbi.nlm.nih.gov/pubmed/27501482
http://dx.doi.org/10.1111/bph.13574