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Robust anti‐nociceptive effects of monoacylglycerol lipase inhibition in a model of osteoarthritis pain
BACKGROUND AND PURPOSE: Chronic pain is often a symptom of knee osteoarthritis (OA) for which current analgesics are either inadequate or are associated with serious side effects. The endocannabinoid system may offer alternative targets for pain relief. We evaluated the effects of a potent and selec...
Autores principales: | Burston, James J, Mapp, Paul I, Sarmad, Sarir, Barrett, David A, Niphakis, Micah J, Cravatt, Benjamin F, Walsh, David A, Chapman, Victoria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056226/ https://www.ncbi.nlm.nih.gov/pubmed/27501482 http://dx.doi.org/10.1111/bph.13574 |
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