Restoring Spinal Noradrenergic Inhibitory Tone Attenuates Pain Hypersensitivity in a Rat Model of Parkinson's Disease

In the present study, we investigated whether restoring descending noradrenergic inhibitory tone can attenuate pain in a PD rat model, which was established by stereotaxic infusion of 6-hydroxydopamine (6-OHDA) into the bilateral striatum (CPu). PD rats developed thermal and mechanical hypersensitiv...

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Detalles Bibliográficos
Autores principales: Cao, Lei-Fang, Peng, Xiao-Yan, Huang, Ya, Wang, Bing, Zhou, Feng-Ming, Cheng, Ruo-Xiao, Chen, Li-Hua, Luo, Wei-Feng, Liu, Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056271/
https://www.ncbi.nlm.nih.gov/pubmed/27747105
http://dx.doi.org/10.1155/2016/6383240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056271/
https://www.ncbi.nlm.nih.gov/pubmed/27747105
http://dx.doi.org/10.1155/2016/6383240

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