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Restoring Spinal Noradrenergic Inhibitory Tone Attenuates Pain Hypersensitivity in a Rat Model of Parkinson's Disease
In the present study, we investigated whether restoring descending noradrenergic inhibitory tone can attenuate pain in a PD rat model, which was established by stereotaxic infusion of 6-hydroxydopamine (6-OHDA) into the bilateral striatum (CPu). PD rats developed thermal and mechanical hypersensitiv...
Autores principales: | Cao, Lei-Fang, Peng, Xiao-Yan, Huang, Ya, Wang, Bing, Zhou, Feng-Ming, Cheng, Ruo-Xiao, Chen, Li-Hua, Luo, Wei-Feng, Liu, Tong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056271/ https://www.ncbi.nlm.nih.gov/pubmed/27747105 http://dx.doi.org/10.1155/2016/6383240 |
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