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Comprehensive Plasma Metabolomic Analyses of Atherosclerotic Progression Reveal Alterations in Glycerophospholipid and Sphingolipid Metabolism in Apolipoprotein E-deficient Mice

Atherosclerosis is the major underlying cause of most cardiovascular diseases. Despite recent advances, the molecular mechanisms underlying the pathophysiology of atherogenesis are not clear. In this study, comprehensive plasma metabolomics were used to investigate early-stage atherosclerotic develo...

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Detalles Bibliográficos
Autores principales: Dang, Vi T., Huang, Aric, Zhong, Lexy H., Shi, Yuanyuan, Werstuck, Geoff H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056345/
https://www.ncbi.nlm.nih.gov/pubmed/27721472
http://dx.doi.org/10.1038/srep35037