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Mesenchymal stem cell therapy ameliorates diabetic nephropathy via the paracrine effect of renal trophic factors including exosomes

Bone marrow-derived mesenchymal stem cells (MSCs) have contributed to the improvement of diabetic nephropathy (DN); however, the actual mediator of this effect and its role has not been characterized thoroughly. We investigated the effects of MSC therapy on DN, focusing on the paracrine effect of re...

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Detalles Bibliográficos
Autores principales: Nagaishi, Kanna, Mizue, Yuka, Chikenji, Takako, Otani, Miho, Nakano, Masako, Konari, Naoto, Fujimiya, Mineko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056395/
https://www.ncbi.nlm.nih.gov/pubmed/27721418
http://dx.doi.org/10.1038/srep34842