A transgenic mouse model expressing an ERα folding biosensor reveals the effects of Bisphenol A on estrogen receptor signaling

Estrogen receptor-α (ERα) plays an important role in normal and abnormal physiology of the human reproductive system by interacting with the endogenous ligand estradiol (E2). However, other ligands, either analogous or dissimilar to E2, also bind to ERα. This may create unintentional activation of E...

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Detalles Bibliográficos
Autores principales: Sekar, Thillai V., Foygel, Kira, Massoud, Tarik F., Gambhir, Sanjiv S., Paulmurugan, Ramasamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056407/
https://www.ncbi.nlm.nih.gov/pubmed/27721470
http://dx.doi.org/10.1038/srep34788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056407/
https://www.ncbi.nlm.nih.gov/pubmed/27721470
http://dx.doi.org/10.1038/srep34788

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