Cargando…

A transgenic mouse model expressing an ERα folding biosensor reveals the effects of Bisphenol A on estrogen receptor signaling

Estrogen receptor-α (ERα) plays an important role in normal and abnormal physiology of the human reproductive system by interacting with the endogenous ligand estradiol (E2). However, other ligands, either analogous or dissimilar to E2, also bind to ERα. This may create unintentional activation of E...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sekar, Thillai V., Foygel, Kira, Massoud, Tarik F., Gambhir, Sanjiv S., Paulmurugan, Ramasamy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056407/ https://www.ncbi.nlm.nih.gov/pubmed/27721470 http://dx.doi.org/10.1038/srep34788

Ejemplares similares

Genetically Encoded Molecular Biosensors To Image Histone Methylation in Living Animals
por: Sekar, Thillai V., et al.
Publicado: (2014)

Monitoring the Antioxidant Mediated Chemosensitization and ARE-Signaling in Triple Negative Breast Cancer Therapy
por: Foygel, Kira, et al.
Publicado: (2015)

A protein folding molecular imaging biosensor monitors the effects of drugs that restore mutant p53 structure and its downstream function in glioblastoma cells
por: Paulmurugan, Ramasamy, et al.
Publicado: (2018)

Polymer Nanoparticles Mediated Codelivery of AntimiR-10b and AntimiR-21 for Achieving Triple Negative Breast Cancer Therapy
por: Devulapally, Rammohan, et al.
Publicado: (2015)

Noninvasive Theranostic Imaging of HSV1-sr39TK-NTR/GCV-CB1954 Dual-Prodrug Therapy in Metastatic Lung Lesions of MDA-MB-231 Triple Negative Breast Cancer in Mice
por: Sekar, Thillai V., et al.
Publicado: (2014)

Degron Protease Blockade Sensor to Image Epigenetic Histone Protein Methylation in Cells and Living Animals
por: Sekar, Thillai V., et al.
Publicado: (2014)

Therapeutic Evaluation of microRNAs by Molecular Imaging
por: Sekar, Thillai V., et al.
Publicado: (2013)

A molecularly engineered split reporter for imaging protein-protein interactions with positron emission tomography
por: Massoud, Tarik F., et al.
Publicado: (2010)

Targeted nanoparticle delivery of therapeutic antisense microRNAs presensitizes glioblastoma cells to lower effective doses of temozolomide in vitro and in a mouse model
por: Malhotra, Meenakshi, et al.
Publicado: (2018)

A Transgenic Tri-Modality Reporter Mouse
por: Yan, Xinrui, et al.
Publicado: (2013)

Formulation of Anti-miR-21 and 4-Hydroxytamoxifen Co-loaded Biodegradable Polymer Nanoparticles and Their Antiproliferative Effect on Breast Cancer Cells
por: Devulapally, Rammohan, et al.
Publicado: (2015)

Bisphenol AF Is a Full Agonist for the Estrogen Receptor ERα but a Highly Specific Antagonist for ERβ
por: Matsushima, Ayami, et al.
Publicado: (2010)

Comparison of cell-based assays to quantify treatment effects of anticancer drugs identifies a new application for Bodipy-L-cystine to measure apoptosis
por: Kumar, Nita, et al.
Publicado: (2018)

SARS-CoV-2 Vaccine Development: An Overview and Perspectives
por: Liu, Yi, et al.
Publicado: (2020)

Biomimetic nanobubbles for triple-negative breast cancer targeted ultrasound molecular imaging
por: Jugniot, Natacha, et al.
Publicado: (2022)

A rationally identified panel of microRNAs targets multiple oncogenic pathways to enhance chemotherapeutic effects in glioblastoma models
por: Sadeghipour, Negar, et al.
Publicado: (2022)

Nrf2 activity as a potential biomarker for the pan-epigenetic anticancer agent, RRx-001
por: Ning, Shoucheng, et al.
Publicado: (2015)

Dynamic Microenvironment Induces Phenotypic Plasticity of Esophageal Cancer Cells Under Flow
por: Calibasi Kocal, Gizem, et al.
Publicado: (2016)

Differential Estrogenic Actions of Endocrine-Disrupting Chemicals Bisphenol A, Bisphenol AF, and Zearalenone through Estrogen Receptor α and β in Vitro
por: Li, Yin, et al.
Publicado: (2012)

Classical Estrogen Receptors and ERα Splice Variants in the Mouse
por: Irsik, Debra L., et al.
Publicado: (2013)

Contrast Enhanced Ultrasound Molecular Imaging of Spontaneous Chronic Inflammatory Bowel Disease in an Interleukin-2 Receptor α(−/−) Transgenic Mouse Model Using Targeted Microbubbles
por: Wang, Huaijun, et al.
Publicado: (2022)

Functions and physiological roles of two types of estrogen receptors, ERα and ERβ, identified by estrogen receptor knockout mouse
por: Lee, Hye-Rim, et al.
Publicado: (2012)

A role for estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ) in collagen biosynthesis in mouse skin
por: Markiewicz, Margaret, et al.
Publicado: (2012)

MMTV-Espl1 Transgenic Mice Develop Aneuploid, Estrogen Receptor Alpha (ERα)-Positive Mammary Adenocarcinomas
por: Mukherjee, Malini, et al.
Publicado: (2013)

Estrogen Signaling in ERα-Negative Breast Cancer: ERβ and GPER
por: Girgert, Rainer, et al.
Publicado: (2019)

Bisphenol-C is the strongest bifunctional ERα-agonist and ERβ-antagonist due to magnified halogen bonding
por: Liu, Xiaohui, et al.
Publicado: (2021)

Human estrogen receptor-α (ER-α) transactivation by selective estrogen receptor modulators (SERMs) on VIT regulatory region in ER-α-negative breast cancer cell line Evsa-T transiently transfected by ER-α
por: Nyamagana Butera, IP, et al.
Publicado: (2001)

The Co-Expression of Estrogen Receptors ERα, ERβ, and GPER in Endometrial Cancer
por: Hojnik, Marko, et al.
Publicado: (2023)

Evolution of BRET Biosensors from Live Cell to Tissue-Scale In vivo Imaging
por: De, Abhijit, et al.
Publicado: (2013)

Transcriptomic analysis identifies gene networks regulated by estrogen receptor α (ERα) and ERβ that control distinct effects of different botanical estrogens
por: Gong, Ping, et al.
Publicado: (2014)

In Vivo Imaging of Activated Estrogen Receptors in Utero by Estrogens and Bisphenol A
por: Lemmen, Josephine G., et al.
Publicado: (2004)

Estrogen receptor independent neurotoxic mechanism of bisphenol A, an environmental estrogen
por: Lee, Yoot Mo, et al.
Publicado: (2007)

Pancreatic Insulin Content Regulation by the Estrogen Receptor ERα
por: Alonso-Magdalena, Paloma, et al.
Publicado: (2008)

Xenoestrogens Alter Estrogen Receptor (ER) α Intracellular Levels
por: La Rosa, Piergiorgio, et al.
Publicado: (2014)

ERα expression in T lymphocytes is dispensable for estrogenic effects in bone
por: Gustafsson, K L, et al.
Publicado: (2018)

Respective role of membrane and nuclear estrogen receptor (ER) α in the mandible of growing mice: Implications for ERα modulation
por: Vinel, Alexia, et al.
Publicado: (2018)

Epigenetic reactivation of estrogen receptor-α (ERα) by genistein enhances hormonal therapy sensitivity in ERα-negative breast cancer
por: Li, Yuanyuan, et al.
Publicado: (2013)

A New Nrf2 Inhibitor Enhances Chemotherapeutic Effects in Glioblastoma Cells Carrying p53 Mutations
por: Afjei, Rayhaneh, et al.
Publicado: (2022)

3D Models of MBP, a Biologically Active Metabolite of Bisphenol A, in Human Estrogen Receptor α and Estrogen Receptor β
por: Baker, Michael E., et al.
Publicado: (2012)

Prevention of Obesity and Insulin Resistance by Estrogens Requires ERα Activation Function-2 (ERαAF-2), Whereas ERαAF-1 Is Dispensable
por: Handgraaf, Sandra, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_rhhlvg8iuk6752u5g50g4gviv5