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A novel ligand of calcitonin receptor reveals a potential new sensor that modulates programmed cell death

We have discovered that the accumulation of an anti-calcitonin receptor (anti-CTR) antibody conjugated to a fluorophore (mAb2C4:AF568) provides a robust signal for cells undergoing apoptotic programmed cell death (PCD). PCD is an absolute requirement for normal development of metazoan organisms. PCD...

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Detalles Bibliográficos
Autores principales: Furness, SGB, Hare, DL, Kourakis, A, Turnley, AM, Wookey, PJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056446/
https://www.ncbi.nlm.nih.gov/pubmed/27777788
http://dx.doi.org/10.1038/cddiscovery.2016.62