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Effects of Fibrinogen Concentrate on Thrombin Generation, Thromboelastometry Parameters, and Laboratory Coagulation Testing in a 24-Hour Porcine Trauma Model

INTRODUCTION: In a 24-hour porcine model of liver injury, we showed that fibrinogen supplementation does not downregulate endogenous fibrinogen synthesis. Here we report data from the same study showing the impact of fibrinogen on coagulation variables. MATERIALS AND METHODS: Coagulopathy was induce...

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Detalles Bibliográficos
Autores principales: Zentai, Christian, Solomon, Cristina, van der Meijden, Paola E. J., Spronk, Henri M. H., Schnabel, Jonas, Rossaint, Rolf, Grottke, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056597/
https://www.ncbi.nlm.nih.gov/pubmed/25948634
http://dx.doi.org/10.1177/1076029615584662