Application of Physiologically Based Absorption Modeling to Characterize the Pharmacokinetic Profiles of Oral Extended Release Methylphenidate Products in Adults

A previously presented physiologically-based pharmacokinetic model for immediate release (IR) methylphenidate (MPH) was extended to characterize the pharmacokinetic behaviors of oral extended release (ER) MPH formulations in adults for the first time. Information on the anatomy and physiology of the...

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Detalles Bibliográficos
Autores principales: Yang, Xiaoxia, Duan, John, Fisher, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056674/
https://www.ncbi.nlm.nih.gov/pubmed/27723791
http://dx.doi.org/10.1371/journal.pone.0164641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056674/
https://www.ncbi.nlm.nih.gov/pubmed/27723791
http://dx.doi.org/10.1371/journal.pone.0164641

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