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A Novel Nuclear Function for the Interleukin-17 Signaling Adaptor Protein Act1

In the context of the human airway, interleukin-17A (IL-17A) signaling is associated with severe inflammation, as well as protection against pathogenic infection, particularly at mucosal surfaces such as the airway. The intracellular molecule Act1 has been demonstrated to be an essential mediator of...

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Detalles Bibliográficos
Autores principales: Velichko, Sharlene, Zhou, Xu, Zhu, Lingxiang, Anderson, Johnathon David, Wu, Reen, Chen, Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056742/
https://www.ncbi.nlm.nih.gov/pubmed/27723765
http://dx.doi.org/10.1371/journal.pone.0163323