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Evaluation of Methionine Content in a High-Fat and Choline-Deficient Diet on Body Weight Gain and the Development of Non-Alcoholic Steatohepatitis in Mice

AIM: Non-alcoholic steatohepatitis (NASH) is a globally recognized liver disease. A methionine- and choline-deficient diet is used to induce NASH in mice; however, this diet also causes severe body weight loss. To resolve this issue, we examined the effects of methionine content in a high-fat and ch...

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Detalles Bibliográficos
Autores principales: Chiba, Tsuyoshi, Suzuki, Sachina, Sato, Yoko, Itoh, Tatsuki, Umegaki, Keizo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056759/
https://www.ncbi.nlm.nih.gov/pubmed/27723801
http://dx.doi.org/10.1371/journal.pone.0164191