Estimating KIR Haplotype Frequencies on a Cohort of 10,000 Individuals: A Comprehensive Study on Population Variations, Typing Resolutions, and Reference Haplotypes

The killer cell immunoglobulin-like receptors (KIR) mediate human natural killer (NK) cell cytotoxicity via activating or inhibiting signals. Although informative and functional haplotype patterns have been reported, most genotyping has been performed at resolutions that are structurally ambiguous....

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Detalles Bibliográficos
Autores principales: Vierra-Green, Cynthia, Roe, David, Jayaraman, Jyothi, Trowsdale, John, Traherne, James, Kuang, Rui, Spellman, Stephen, Maiers, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056762/
https://www.ncbi.nlm.nih.gov/pubmed/27723813
http://dx.doi.org/10.1371/journal.pone.0163973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056762/
https://www.ncbi.nlm.nih.gov/pubmed/27723813
http://dx.doi.org/10.1371/journal.pone.0163973

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