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Intrinsic Resistance to 5-Fluorouracil in a Brain Metastatic Variant of Human Breast Cancer Cell Line, MDA-MB-231BR

Although drug resistance is often observed in metastatic recurrence of breast cancer, little is known about the intrinsic drug resistance in such metastases. In the present study, we found, for the first time, that MDA-MB-231BR, a brain metastatic variant of a human breast cancer cell line, was refr...

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Detalles Bibliográficos
Autores principales: Sagara, Atsunobu, Igarashi, Katsuhide, Otsuka, Maky, Karasawa, Takeshi, Gotoh, Noriko, Narita, Michiko, Kuzumaki, Naoko, Narita, Minoru, Kato, Yoshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056764/
https://www.ncbi.nlm.nih.gov/pubmed/27723829
http://dx.doi.org/10.1371/journal.pone.0164250