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Aminoglycoside-stimulated readthrough of premature termination codons in selected genes involved in primary ciliary dyskinesia

Translational readthrough of premature termination codons (PTCs) induced by pharmacological compounds has proven to be an effective way of restoring functional protein expression and reducing symptoms in several genetic disorders. We tested the potential of different concentrations of several aminog...

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Detalles Bibliográficos
Autores principales: Bukowy-Bieryllo, Zuzanna, Dabrowski, Maciej, Witt, Michał, Zietkiewicz, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056772/
https://www.ncbi.nlm.nih.gov/pubmed/27618201
http://dx.doi.org/10.1080/15476286.2016.1219832