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lncRNA profiling in early-stage chronic lymphocytic leukemia identifies transcriptional fingerprints with relevance in clinical outcome

Long non-coding RNAs (lncRNAs) represent a novel class of functional RNA molecules with an important emerging role in cancer. To elucidate their potential pathogenetic role in chronic lymphocytic leukemia (CLL), a biologically and clinically heterogeneous neoplasia, we investigated lncRNAs expressio...

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Detalles Bibliográficos
Autores principales: Ronchetti, D, Manzoni, M, Agnelli, L, Vinci, C, Fabris, S, Cutrona, G, Matis, S, Colombo, M, Galletti, S, Taiana, E, Recchia, A G, Bossio, S, Gentile, M, Musolino, C, Di Raimondo, F, Grilli, A, Bicciato, S, Cortelezzi, A, Tassone, P, Morabito, F, Ferrarini, M, Neri, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056969/
https://www.ncbi.nlm.nih.gov/pubmed/27611921
http://dx.doi.org/10.1038/bcj.2016.77