Aldehyde dehydrogenases inhibition eradicates leukemia stem cells while sparing normal progenitors

The vast majority of patients with acute myeloid leukemia (AML) achieve complete remission (CR) after standard induction chemotherapy. However, the majority subsequently relapse and die of the disease. A leukemia stem cell (LSC) paradigm has been invoked to explain this failure of CR to reliably tra...

Descripción completa

Detalles Bibliográficos
Autores principales: Venton, G, Pérez-Alea, M, Baier, C, Fournet, G, Quash, G, Labiad, Y, Martin, G, Sanderson, F, Poullin, P, Suchon, P, Farnault, L, Nguyen, C, Brunet, C, Ceylan, I, Costello, R T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056970/
https://www.ncbi.nlm.nih.gov/pubmed/27611922
http://dx.doi.org/10.1038/bcj.2016.78

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056970/
https://www.ncbi.nlm.nih.gov/pubmed/27611922
http://dx.doi.org/10.1038/bcj.2016.78

Ejemplares similares