Targeting Insulin Receptor with a Novel Internalizing Aptamer

Nucleic acid-based aptamers are emerging as therapeutic antagonists of disease-associated proteins such as receptor tyrosine kinases. They are selected by an in vitro combinatorial chemistry approach, named Systematic Evolution of Ligands by Exponential enrichment (SELEX), and thanks to their small...

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Detalles Bibliográficos
Autores principales: Iaboni, Margherita, Fontanella, Raffaela, Rienzo, Anna, Capuozzo, Maria, Nuzzo, Silvia, Santamaria, Gianluca, Catuogno, Silvia, Condorelli, Gerolama, de Franciscis, Vittorio, Esposito, Carla Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056995/
https://www.ncbi.nlm.nih.gov/pubmed/27648925
http://dx.doi.org/10.1038/mtna.2016.73

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056995/
https://www.ncbi.nlm.nih.gov/pubmed/27648925
http://dx.doi.org/10.1038/mtna.2016.73

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