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Olfactomedin 4 deletion induces colon adenocarcinoma in Apc(Min/+) mice

Colon carcinogenesis is a multiple-step process involving the accumulation of a series of genetic and epigenetic alterations. The most commonly initiating event of intestinal carcinogenesis is mutation of the adenomatous polyposis coli (APC) gene, which leads to activation of the Wnt/β-catenin pathw...

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Detalles Bibliográficos
Autores principales: Liu, W, Li, H, Hong, S-H, Piszczek, G P, Chen, W, Rodgers, G P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5057043/
https://www.ncbi.nlm.nih.gov/pubmed/26973250
http://dx.doi.org/10.1038/onc.2016.58