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Hepatocellular Carcinoma-propagating Cells are Detectable by Side Population Analysis and Possess an Expression Profile Reflective of a Primitive Origin

The recent identification of “Side Population” (SP) cells in a number of unrelated human cancers has renewed interests in the hypothesis of cancer stem cells. Here we isolated SP cells from HepG2 cells and 18 of the 21 fresh hepatocellular carcinoma (HCC) tissue samples. These SP cells have higher a...

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Detalles Bibliográficos
Autores principales: Xia, Honghai, Cao, Jun, Li, Qing, Lv, Yang, Jia, Weidong, Ren, Weihua, Cheng, Qingyu, Song, Xiaoyuan, Xu, Geliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5057076/
https://www.ncbi.nlm.nih.gov/pubmed/27725724
http://dx.doi.org/10.1038/srep34856