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Fabrication of an antibody-aptamer sandwich assay for electrochemical evaluation of levels of β-amyloid oligomers

Amyloid β-peptide (Aβ) in its oligomeric form is often considered as the most toxic species in Alzheimer’s disease (AD), and thus Aβ oligomer is a potentially promising candidate biomarker for AD diagnosis. The development of a sensitive and reliable method for monitoring the Aβ oligomer levels in b...

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Detalles Bibliográficos
Autores principales: Zhou, Yanli, Zhang, Huanqing, Liu, Lantao, Li, Congming, Chang, Zhu, Zhu, Xu, Ye, Baoxian, Xu, Maotian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5057102/
https://www.ncbi.nlm.nih.gov/pubmed/27725775
http://dx.doi.org/10.1038/srep35186