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DNA N(6)-methyladenine demethylase ALKBH1 enhances osteogenic differentiation of human MSCs

ALKBH1 was recently discovered as a demethylase for DNA N(6)-methyladenine (N6-mA), a new epigenetic modification, and interacts with the core transcriptional pluripotency network of embryonic stem cells. However, the role of ALKBH1 and DNA N6-mA in regulating osteogenic differentiation is largely u...

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Detalles Bibliográficos
Autores principales: Zhou, Chenchen, Liu, Yuting, Li, Xiaobing, Zou, Jing, Zou, Shujuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5057179/
https://www.ncbi.nlm.nih.gov/pubmed/27785372
http://dx.doi.org/10.1038/boneres.2016.33