Cerebral hypoxia/ischemia selectively disrupts tight junctions complexes in stem cell-derived human brain microvascular endothelial cells

BACKGROUND: Cerebral hypoxia/ischemia (H/I) is an important stress factor involved in the disruption of the blood–brain barrier (BBB) following stroke injury, yet the cellular and molecular mechanisms on how the human BBB responds to such injury remains unclear. In this study, we investigated the ce...

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Detalles Bibliográficos
Autores principales: Page, Shyanne, Munsell, Alli, Al-Ahmad, Abraham J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5057206/
https://www.ncbi.nlm.nih.gov/pubmed/27724968
http://dx.doi.org/10.1186/s12987-016-0042-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5057206/
https://www.ncbi.nlm.nih.gov/pubmed/27724968
http://dx.doi.org/10.1186/s12987-016-0042-1

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