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Pulmonary artery denervation improves pulmonary arterial hypertension induced right ventricular dysfunction by modulating the local renin-angiotensin-aldosterone system

BACKGROUND: Pulmonary arterial hypertension (PAH) is commonly accompanied with the activation of the renin-angiotensin-aldosterone system (RAAS). Renal sympathetic denervation (RSD) reduces PAH partly through the inhibition of RAAS. Analogically, we hypothesized that pulmonary artery denervation (PA...

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Detalles Bibliográficos
Autores principales: Liu, Chen, Jiang, Xiao-Min, Zhang, Juan, Li, Bing, Li, Jing, Xie, Du-Jiang, Hu, Zuo-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5057227/
https://www.ncbi.nlm.nih.gov/pubmed/27724864
http://dx.doi.org/10.1186/s12872-016-0366-4