Cargando…
Nuclear envelope rupture is induced by actin-based nucleus confinement
Repeated rounds of nuclear envelope (NE) rupture and repair have been observed in laminopathy and cancer cells and result in intermittent loss of nucleus compartmentalization. Currently, the causes of NE rupture are unclear. Here, we show that NE rupture in cancer cells relies on the assembly of con...
Autores principales: | Hatch, Emily M., Hetzer, Martin W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5057282/ https://www.ncbi.nlm.nih.gov/pubmed/27697922 http://dx.doi.org/10.1083/jcb.201603053 |
Ejemplares similares
-
Nuclear envelope rupture: Actin fibers are putting the squeeze on the nucleus
por: Lammerding, Jan, et al.
Publicado: (2016) -
Breaching the nuclear envelope in development and disease
por: Hatch, Emily, et al.
Publicado: (2014) -
Automated analysis of cell migration and nuclear envelope rupture in confined environments
por: Elacqua, Joshua J., et al.
Publicado: (2018) -
Reshaping of the endoplasmic reticulum limits the rate for nuclear envelope formation
por: Anderson, Daniel J., et al.
Publicado: (2008) -
Actin assembly ruptures the nuclear envelope by prying the lamina away from nuclear pores and nuclear membranes in starfish oocytes
por: Wesolowska, Natalia, et al.
Publicado: (2020)