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ASB7 regulates spindle dynamics and genome integrity by targeting DDA3 for proteasomal degradation

Proper dynamic regulation of the spindle is essential for successful cell division. However, the molecular mechanisms that regulate spindle dynamics in mitosis are not fully understood. In this study, we show that Cullin 5–interacting suppressor of cytokine signaling box protein ASB7 ubiquitinates D...

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Detalles Bibliográficos
Autores principales: Uematsu, Keiji, Okumura, Fumihiko, Tonogai, Syunsuke, Joo-Okumura, Akiko, Alemayehu, Dawit Hailu, Nishikimi, Akihiko, Fukui, Yoshinori, Nakatsukasa, Kunio, Kamura, Takumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5057283/
https://www.ncbi.nlm.nih.gov/pubmed/27697924
http://dx.doi.org/10.1083/jcb.201603062