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Neutrophil mechanotransduction: A GEF to sense fluid shear stress

Forces deriving from blood flow shear modulate vascular adherence and transendothelial migration of leukocytes into inflamed tissues, but the mechanisms by which shear is sensed are unclear. In this issue, Fine et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201603109) identify the guanosi...

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Detalles Bibliográficos
Autor principal: Niethammer, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5057290/
https://www.ncbi.nlm.nih.gov/pubmed/27738002
http://dx.doi.org/10.1083/jcb.201609101