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GREM 1 and POLE variants in hereditary colorectal cancer syndromes

Hereditary factors are thought to play a role in at least one third of patients with colorectal cancer (CRC) but only a limited proportion of these have mutations in known high‐penetrant genes. In a relatively large part of patients with a few or multiple colorectal polyps the underlying genetic cau...

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Detalles Bibliográficos
Autores principales: Rohlin, Anna, Eiengård, Frida, Lundstam, Ulf, Zagoras, Theofanis, Nilsson, Staffan, Edsjö, Anders, Pedersen, Jan, Svensson, Janhenry, Skullman, Stefan, Karlsson, B. Göran, Björk, Jan, Nordling, Margareta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5057327/
https://www.ncbi.nlm.nih.gov/pubmed/26493165
http://dx.doi.org/10.1002/gcc.22314