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The Effect of Fingolimod on Conversion of Acute Gadolinium‐Enhancing Lesions to Chronic T1 Hypointensities in Multiple Sclerosis

BACKGROUND: Brain lesions converting to chronic T1 hypointensities (“chronic black holes” [CBH]), indicate severe tissue destruction (axonal loss and irreversible demyelination) in multiple sclerosis (MS). Two mechanisms by which fingolimod could limit MS lesion evolution include sequestration of ly...

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Detalles Bibliográficos
Autores principales: Oommen, Vinit V., Tauhid, Shahamat, Healy, Brian C., Chua, Alicia S., Malik, Muhammad T., Diaz‐Cruz, Camilo, Dupuy, Sheena L., Weiner, Howard L., Chitnis, Tanuja, Bakshi, Rohit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5057343/
https://www.ncbi.nlm.nih.gov/pubmed/26445919
http://dx.doi.org/10.1111/jon.12307