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Differential TLR activation of murine mesenchymal stem cells generates distinct immunomodulatory effects in EAE

BACKGROUND: Recently, it has been observed that mesenchymal stem cells (MSCs) can modulate their immunoregulatory properties depending on the specific in-vitro activation of different Toll-like receptors (TLR), such as TLR3 and TLR4. In the present study, we evaluated the effect of polyinosinic:poly...

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Detalles Bibliográficos
Autores principales: Vega-Letter, Ana María, Kurte, Mónica, Fernández-O’Ryan, Catalina, Gauthier-Abeliuk, Melanie, Fuenzalida, Patricia, Moya-Uribe, Ivón, Altamirano, Claudia, Figueroa, Fernando, Irarrázabal, Carlos, Carrión, Flavio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5057482/
https://www.ncbi.nlm.nih.gov/pubmed/27724984
http://dx.doi.org/10.1186/s13287-016-0402-4