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Histone modification signature at myeloperoxidase and proteinase 3 in patients with anti-neutrophil cytoplasmic autoantibody-associated vasculitis

BACKGROUND: Anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV) is a systemic autoimmune disease characterized by destructive vascular inflammation. Two prominent ANCA autoantigens are myeloperoxidase (MPO) and proteinase 3 (PR3), and transcription of MPO and PRTN3, the genes...

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Detalles Bibliográficos
Autores principales: Yang, Jiajin, Ge, Heng, Poulton, Caroline J., Hogan, Susan L., Hu, Yichun, Jones, Britta E., Henderson, Candace D., McInnis, Elizabeth A., Pendergraft, William F., Jennette, J. Charles, Falk, Ronald J., Ciavatta, Dominic J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5057507/
https://www.ncbi.nlm.nih.gov/pubmed/27752292
http://dx.doi.org/10.1186/s13148-016-0251-0