Sarkosyl-Induced Helical Structure of an Antimicrobial Peptide GW-Q6 Plays an Essential Role in the Binding of Surface Receptor OprI in Pseudomonas aeruginosa

The emergence of antibiotic-resistant microbial strains has become a public health issue and there is an urgent need to develop new anti-infective molecules. Although natural antimicrobial peptides (AMPs) can exert bactericidal activities, they have not shown clinical efficacy. The limitations of na...

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Detalles Bibliográficos
Autores principales: Tseng, Tien-Sheng, Wang, Shih-Han, Chang, Ting-Wei, Wei, Hung-Mu, Wang, Yu-June, Tsai, Keng-Chang, Liao, You-Di, Chen, Chinpan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058510/
https://www.ncbi.nlm.nih.gov/pubmed/27727309
http://dx.doi.org/10.1371/journal.pone.0164597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058510/
https://www.ncbi.nlm.nih.gov/pubmed/27727309
http://dx.doi.org/10.1371/journal.pone.0164597

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