High affinity nanobodies against human epidermal growth factor receptor selected on cells by E. coli display

Most therapeutic antibodies (Abs) target cell surface proteins on tumor and immune cells. Cloning of Ab gene libraries in E. coli and their display on bacteriophages is commonly used to select novel therapeutic Abs binding target antigens, either purified or expressed on cells. However, the sticky n...

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Detalles Bibliográficos
Autores principales: Salema, Valencio, Mañas, Carmen, Cerdán, Lidia, Piñero-Lambea, Carlos, Marín, Elvira, Roovers, Rob C., Van Bergen en Henegouwen, Paul M.P., Fernández, Luis Ángel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058628/
https://www.ncbi.nlm.nih.gov/pubmed/27472381
http://dx.doi.org/10.1080/19420862.2016.1216742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058628/
https://www.ncbi.nlm.nih.gov/pubmed/27472381
http://dx.doi.org/10.1080/19420862.2016.1216742

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