Characterizing monoclonal antibody formulations in arginine glutamate solutions using (1)H NMR spectroscopy

Assessing how excipients affect the self-association of monoclonal antibodies (mAbs) requires informative and direct in situ measurements for highly concentrated solutions, without sample dilution or perturbation. This study explores the application of solution nuclear magnetic resonance (NMR) spect...

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Detalles Bibliográficos
Autores principales: Kheddo, Priscilla, Cliff, Matthew J., Uddin, Shahid, van der Walle, Christopher F., Golovanov, Alexander P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058632/
https://www.ncbi.nlm.nih.gov/pubmed/27589351
http://dx.doi.org/10.1080/19420862.2016.1214786

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058632/
https://www.ncbi.nlm.nih.gov/pubmed/27589351
http://dx.doi.org/10.1080/19420862.2016.1214786

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