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Human prion protein-induced autophagy flux governs neuron cell damage in primary neuron cells

An unusual molecular structure of the prion protein, PrPsc is found only in mammals with transmissible prion diseases. Prion protein stands for either the infectious pathogen itself or a main component of it. Recent studies suggest that autophagy is one of the major functions that keep cells alive a...

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Detalles Bibliográficos
Autores principales: Moon, Ji-Hong, Lee, Ju-Hee, Nazim, Uddin MD, Lee, You-Jin, Seol, Jae-Won, Eo, Seong-Kug, Lee, John-hwa, Park, Sang-Youel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058658/
https://www.ncbi.nlm.nih.gov/pubmed/27102156
http://dx.doi.org/10.18632/oncotarget.8802