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Routine clinical mutation profiling using next generation sequencing and a customized gene panel improves diagnostic precision in myeloid neoplasms

Microscopic examination of myelodysplastic syndromes (MDS) and myelodysplastic-myeloproliferative neoplasms (MDS/MPN) may be challenging because morphological features can overlap with those of reactive states. Demonstration of clonal hematopoiesis provides a diagnostic clue and has become possible...

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Detalles Bibliográficos
Autores principales: Bartels, Stephan, Schipper, Elisa, Hasemeier, Britta, Kreipe, Hans, Lehmann, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058665/
https://www.ncbi.nlm.nih.gov/pubmed/27029036
http://dx.doi.org/10.18632/oncotarget.8310