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Human mesenchymal stromal cell-secreted lactate induces M2-macrophage differentiation by metabolic reprogramming

Human mesenchymal stromal cells (MSC) have been shown to dampen immune response and promote tissue repair, but the underlying mechanisms are still under investigation. Herein, we demonstrate that umbilical cord-derived MSC (UC-MSC) alter the phenotype and function of monocyte-derived dendritic cells...

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Detalles Bibliográficos
Autores principales: Selleri, Silvia, Bifsha, Panojot, Civini, Sara, Pacelli, Consiglia, Dieng, Mame Massar, Lemieux, William, Jin, Ping, Bazin, Renée, Patey, Natacha, Marincola, Francesco M., Moldovan, Florina, Zaouter, Charlotte, Trudeau, Louis-Eric, Benabdhalla, Basma, Louis, Isabelle, Beauséjour, Christian, Stroncek, David, Le Deist, Françoise, Haddad, Elie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058674/
https://www.ncbi.nlm.nih.gov/pubmed/27070086
http://dx.doi.org/10.18632/oncotarget.8623