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Vinca alkaloid drugs promote stress-induced translational repression and stress granule formation

Resistance to chemotherapy drugs is a serious therapeutic problem and its underlying molecular mechanisms are complex. Stress granules (SGs), cytoplasmic ribonucleoprotein complexes assembled in cells exposed to stress, are implicated in various aspects of cancer cell metabolism and survival. SGs pr...

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Detalles Bibliográficos
Autores principales: Szaflarski, Witold, Fay, Marta M., Kedersha, Nancy, Zabel, Maciej, Anderson, Paul, Ivanov, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058682/
https://www.ncbi.nlm.nih.gov/pubmed/27083003
http://dx.doi.org/10.18632/oncotarget.8728