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Thin and thick primary cutaneous melanomas reveal distinct patterns of somatic copy number alterations

Cutaneous melanoma is one of the most aggressive type of skin tumor. Early stage melanoma can be often cured by surgery; therefore current management guidelines dictate a different approach for thin (<1mm) versus thick (>4mm) melanomas. We have carried out whole-exome sequencing in 5 thin and...

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Detalles Bibliográficos
Autores principales: Montagnani, Valentina, Benelli, Matteo, Apollo, Alessandro, Pescucci, Chiara, Licastro, Danilo, Urso, Carmelo, Gerlini, Gianni, Borgognoni, Lorenzo, Luzzatto, Lucio, Stecca, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058686/
https://www.ncbi.nlm.nih.gov/pubmed/27095580
http://dx.doi.org/10.18632/oncotarget.8758