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Abnormal lipid processing but normal long-term repopulation potential of myc−/− hepatocytes

Establishing c-Myc's (Myc) role in liver regeneration has proven difficult particularly since the traditional model of partial hepatectomy may provoke an insufficiently demanding proliferative stress. We used a model of hereditary tyrosinemia whereby the affected parenchyma can be gradually rep...

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Detalles Bibliográficos
Autores principales: Edmunds, Lia R., Otero, P. Anthony, Sharma, Lokendra, D'souza, Sonia, Dolezal, James M., David, Sherin, Lu, Jie, Lamm, Lauren, Basantani, Mahesh, Zhang, Pili, Sipula, Ian J., Li, Lucy, Zeng, Xuemei, Ding, Ying, Ding, Fei, Beck, Megan E., Vockley, Jerry, Monga, Satdarshan P. S., Kershaw, Erin E., O'Doherty, Robert M., Kratz, Lisa E., Yates, Nathan A., Goetzman, Eric P., Scott, Donald, Duncan, Andrew W., Prochownik, Edward V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058687/
https://www.ncbi.nlm.nih.gov/pubmed/27105497
http://dx.doi.org/10.18632/oncotarget.8856