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Salinomycin induced ROS results in abortive autophagy and leads to regulated necrosis in glioblastoma

Glioblastoma is the most frequent malignant brain tumor. Even with aggressive treatment, prognosis for patients is poor. One characteristic of glioblastoma cells is its intrinsic resistance to apoptosis. Therefore, drugs that induce alternative cell deaths could be interesting to evaluate as alterna...

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Detalles Bibliográficos
Autores principales: Xipell, Enric, Gonzalez-Huarriz, Marisol, de Irujo, Juan Jose Martinez, García-Garzón, Antonia, Lang, Fred F., Jiang, Hong, Fueyo, Juan, Gomez-Manzano, Candelaria, Alonso, Marta M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058706/
https://www.ncbi.nlm.nih.gov/pubmed/27121320
http://dx.doi.org/10.18632/oncotarget.8905