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Salinomycin induced ROS results in abortive autophagy and leads to regulated necrosis in glioblastoma
Glioblastoma is the most frequent malignant brain tumor. Even with aggressive treatment, prognosis for patients is poor. One characteristic of glioblastoma cells is its intrinsic resistance to apoptosis. Therefore, drugs that induce alternative cell deaths could be interesting to evaluate as alterna...
Autores principales: | Xipell, Enric, Gonzalez-Huarriz, Marisol, de Irujo, Juan Jose Martinez, García-Garzón, Antonia, Lang, Fred F., Jiang, Hong, Fueyo, Juan, Gomez-Manzano, Candelaria, Alonso, Marta M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058706/ https://www.ncbi.nlm.nih.gov/pubmed/27121320 http://dx.doi.org/10.18632/oncotarget.8905 |
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