Palmitoylated claudin7 captured in glycolipid-enriched membrane microdomains promotes metastasis via associated transmembrane and cytosolic molecules

In epithelial cells claudin7 (cld7) is a major component of tight junctions, but is also recovered from glycolipid-enriched membrane microdomains (GEM). In tumor cells, too, cld7 exists in two stages. Only GEM-located cld7, which is palmitoylated, promotes metastasis. Searching for the underlying me...

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Detalles Bibliográficos
Autores principales: Thuma, Florian, Heiler, Sarah, Schnölzer, Martina, Zöller, Margot
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058708/
https://www.ncbi.nlm.nih.gov/pubmed/27120791
http://dx.doi.org/10.18632/oncotarget.8928

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058708/
https://www.ncbi.nlm.nih.gov/pubmed/27120791
http://dx.doi.org/10.18632/oncotarget.8928

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