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PIK3CA amplification is associated with poor prognosis among patients with curatively resected esophageal squamous cell carcinoma

To investigate the clinicopathologic characteristics and the prognostic impact of PIK3CA gene amplification in curatively resected esophageal squamous cell carcinoma (ESCC). Using 534 curatively resected ESCCs, the PIK3CA gene copy number was evaluated with fluorescent in situ hybridization. PIK3CA...

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Detalles Bibliográficos
Autores principales: Kim, Hyo Song, Lee, Seung Eun, Bae, Yoon Sung, Kim, Dae Joon, Lee, Chang Geol, Hur, Jin, Chung, Hyunsoo, Park, Jun Chul, Shin, Sung Kwan, Lee, Sang Kil, Lee, Yong Chan, Kim, Hye Ryun, Shim, Young Mog, Jewell, Susan S., Kim, Hyunki, Choi, Yoon-La, Cho, Byoung Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058710/
https://www.ncbi.nlm.nih.gov/pubmed/27095573
http://dx.doi.org/10.18632/oncotarget.8749