Cargando…

PIK3CA amplification is associated with poor prognosis among patients with curatively resected esophageal squamous cell carcinoma

To investigate the clinicopathologic characteristics and the prognostic impact of PIK3CA gene amplification in curatively resected esophageal squamous cell carcinoma (ESCC). Using 534 curatively resected ESCCs, the PIK3CA gene copy number was evaluated with fluorescent in situ hybridization. PIK3CA...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Hyo Song, Lee, Seung Eun, Bae, Yoon Sung, Kim, Dae Joon, Lee, Chang Geol, Hur, Jin, Chung, Hyunsoo, Park, Jun Chul, Shin, Sung Kwan, Lee, Sang Kil, Lee, Yong Chan, Kim, Hye Ryun, Shim, Young Mog, Jewell, Susan S., Kim, Hyunki, Choi, Yoon-La, Cho, Byoung Chul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058710/ https://www.ncbi.nlm.nih.gov/pubmed/27095573 http://dx.doi.org/10.18632/oncotarget.8749

Ejemplares similares

Fibroblast growth factor receptor 1 gene amplification is associated with poor survival in patients with resected esophageal squamous cell carcinoma
por: Kim, Hyo Song, et al.
Publicado: (2014)

Prognostic implications of PIK3CA amplification in curatively resected liposarcoma
por: Kim, Joo Hoon, et al.
Publicado: (2016)

Phase II clinical and exploratory biomarker study of dacomitinib in recurrent and/or metastatic esophageal squamous cell carcinoma
por: Kim, Hyo Song, et al.
Publicado: (2015)

Optimal Adjuvant Treatment for Curatively Resected Thoracic Esophageal Squamous Cell Carcinoma: A Radiotherapy Perspective
por: Kim, Kyung Hwan, et al.
Publicado: (2017)

Postoperative Helicobacter pylori Infection as a Prognostic Factor for Gastric Cancer Patients after Curative Resection
por: Jung, Da Hyun, et al.
Publicado: (2017)

High CD3 and ICOS and low TIM-3 expression predict favourable survival in resected oesophageal squamous cell carcinoma
por: Hong, Min Hee, et al.
Publicado: (2019)

The feasibility and safety of radical esophagectomy in patients receiving neoadjuvant chemoradiotherapy with pembrolizumab for esophageal squamous cell carcinoma
por: Park, Seong Yong, et al.
Publicado: (2020)

Dose-Response Relationship between Radiation Dose and Loco-regional Control in Patients with Stage II-III Esophageal Cancer Treated with Definitive Chemoradiotherapy
por: Kim, Hyun Ju, et al.
Publicado: (2017)

Amplification of distinct α-synuclein fibril conformers through protein misfolding cyclic amplification
por: Jung, Byung Chul, et al.
Publicado: (2017)

Screening of ROS1 Rearrangements in Lung Adenocarcinoma by Immunohistochemistry and Comparison with ALK Rearrangements
por: Cha, Yoon Jin, et al.
Publicado: (2014)

Predicting Recurrence Using the Clinical Factors of Patients with Non-small Cell Lung Cancer After Curative Resection
por: Lee, Hyun Joo, et al.
Publicado: (2009)

PIK3CA Amplification Is Common in Left Side-Tubular Adenomas but Uncommon Sessile Serrated Adenomas Exclusively with KRAS Mutation
por: Lee, Hyunsu, et al.
Publicado: (2015)

Intracranial failure after hippocampal-avoidance prophylactic cranial irradiation in limited-stage small-cell lung cancer patients
por: Cho, Yeona, et al.
Publicado: (2021)

Role of Chemotherapy in Stage II Nasopharyngeal Carcinoma Treated with Curative Radiotherapy
por: Kang, Min Kyu, et al.
Publicado: (2015)

ERRATUM: Role of Chemotherapy in Stage II Nasopharyngeal Carcinoma Treated with Curative Radiotherapy
por: Kang, Min Kyu, et al.
Publicado: (2016)

Increased Incidence of Endoscopic Erosive Esophagitis in Solid Organ Transplant Recipients
por: Kim, In Soo, et al.
Publicado: (2012)

Conditional Survival of Patients Who Underwent Curative Resection for Esophageal Squamous Cell Carcinoma
por: Shin, Dong Wook, et al.
Publicado: (2022)

One-Week versus Two-Week Chemoradiotherapy Followed by Curative Surgery in Rectal Cancer: Long-Term Comparative Pooled Analysis of Two Prospective Multicenter Phase II Trials
por: Sung, Soo-Yoon, et al.
Publicado: (2023)

Prognostic Model to Predict Survival Outcome for Curatively Resected Liposarcoma: A Multi-Institutional Experience
por: Oh, Yoon Jung, et al.
Publicado: (2016)

Clinical Outcomes of Endoscopic Hemostasis for Bleeding in Patients with Unresectable Advanced Gastric Cancer
por: Song, In Ji, et al.
Publicado: (2017)

Achalasia Combined with Esophageal Cancer Treated by Concurrent Chemoradiation Therapy
por: Park, Jun Chul, et al.
Publicado: (2009)

Machine Learning Improves the Prediction Rate of Non-Curative Resection of Endoscopic Submucosal Dissection in Patients with Early Gastric Cancer
por: Yun, Hae-Ryong, et al.
Publicado: (2022)

Sample Collection Methods in Upper Gastrointestinal Research
por: Yang, Hyo-Joon, et al.
Publicado: (2023)

Significance of druggable targets (PD-L1, KRAS, BRAF, PIK3CA, MSI, and HPV) on curatively resected esophageal squamous cell carcinoma
por: Lee, Hong Kyu, et al.
Publicado: (2020)

Distinct Characteristics and Clinical Outcomes to Predict the Emergence of MET Amplification in Patients with Non-Small Cell Lung Cancer Who Developed Resistance after Treatment with Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors
por: Ahn, Beung-Chul, et al.
Publicado: (2021)

Screening for Chlamydia and Gonorrhea by Strand Displacement Amplification in Homeless Adolescents Attending Youth Shelters in Korea
por: Lee, Seung-Ju, et al.
Publicado: (2004)

Comprehensive expression profiles of gastric cancer molecular subtypes by immunohistochemistry: implications for individualized therapy
por: Kim, Hyo Song, et al.
Publicado: (2016)

Optimal dose and volume for postoperative radiotherapy in brain oligometastases from lung cancer: a retrospective study
por: Chung, Seung Yeun, et al.
Publicado: (2017)

Detection of activating and acquired resistant mutation in plasma from EGFR-mutated NSCLC patients by peptide nucleic acid (PNA) clamping-assisted fluorescence melting curve analysis
por: Kim, Chang Gon, et al.
Publicado: (2017)

Endoscopic Management of Gastrointestinal Leaks and Perforation with Polyglycolic Acid Sheets
por: Han, Sojung, et al.
Publicado: (2017)

Surgical Resection of Recurrent Lung Cancer in Patients Following Curative Resection
por: Kim, Hyoung Soo, et al.
Publicado: (2006)

The Capsicum annuum class IV chitinase ChitIV interacts with receptor-like cytoplasmic protein kinase PIK1 to accelerate PIK1-triggered cell death and defence responses
por: Kim, Dae Sung, et al.
Publicado: (2015)

A Case of Coarctation of the Aorta Diagnosed by Tardus-Parvus Renal Doppler Flow Patterns
por: Jung, Yun-Hwa, et al.
Publicado: (2011)

A comparison of the accuracy of ulnar versus median nerve stimulation for neuromuscular monitoring
por: Lee, Hee Jong, et al.
Publicado: (2011)

Low Incidence of Synchronous or Metachronous Tumors after Endoscopic Submucosal Dissection for Early Gastric Cancer with Undifferentiated Histology
por: Park, Chan Hyuk, et al.
Publicado: (2016)

Circumferential Resection Margin Involvement in Stage III Rectal Cancer Patients Treated with Curative Resection Followed by Chemoradiotherapy: A Surrogate Marker for Local Recurrence?
por: Kang, Jeonghyun, et al.
Publicado: (2013)

Mutant PIK3CA as a negative predictive biomarker for treatment with a highly selective PIM1 inhibitor in human colon cancer
por: Park, Yoon Sun, et al.
Publicado: (2023)

Predicting treatment outcomes using (18)F-FDG PET biomarkers in patients with non-small-cell lung cancer receiving chemoimmunotherapy
por: Kim, Chang Gon, et al.
Publicado: (2022)

Esophageal Leiomyoma: Radiologic Findings in 12 Patients
por: Yang, Po Song, et al.
Publicado: (2001)

Recurrence dynamics after curative surgery in patients with invasive mucinous adenocarcinoma of the lung
por: Yoon, Hyun Jung, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_6jepemacapvbn5hvgjnkhu94al