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SRC kinase inhibition with saracatinib limits the development of osteolytic bone disease in multiple myeloma
Multiple myeloma (MM)-associated osteolytic bone disease is a major cause of morbidity and mortality in MM patients and the development of new therapeutic strategies is of great interest. The proto-oncogene SRC is an attractive target for such a strategy. In the current study, we investigated the ef...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058712/ https://www.ncbi.nlm.nih.gov/pubmed/27095574 http://dx.doi.org/10.18632/oncotarget.8750 |