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Altered oncomodules underlie chromatin regulatory factors driver mutations

Chromatin regulatory factors (CRFs), are known to be involved in tumorigenesis in several cancer types. Nevertheless, the molecular mechanisms through which driver alterations of CRFs cause tumorigenesis remain unknown. Here, we developed a CRFs Oncomodules Discovery approach, which mines several so...

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Detalles Bibliográficos
Autores principales: Frigola, Joan, Iturbide, Ane, Lopez-Bigas, Nuria, Peiro, Sandra, Gonzalez-Perez, Abel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058714/
https://www.ncbi.nlm.nih.gov/pubmed/27095575
http://dx.doi.org/10.18632/oncotarget.8752