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KCa3.1 channel inhibition sensitizes malignant gliomas to temozolomide treatment

Malignant gliomas are among the most frequent and aggressive cerebral tumors, characterized by high proliferative and invasive indexes. Standard therapy for patients, after surgery and radiotherapy, consists of temozolomide (TMZ), a methylating agent that blocks tumor cell proliferation. Currently,...

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Detalles Bibliográficos
Autores principales: D'Alessandro, Giuseppina, Grimaldi, Alfonso, Chece, Giuseppina, Porzia, Alessandra, Esposito, Vincenzo, Santoro, Antonio, Salvati, Maurizio, Mainiero, Fabrizio, Ragozzino, Davide, Angelantonio, Silvia Di, Wulff, Heike, Catalano, Myriam, Limatola, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058717/
https://www.ncbi.nlm.nih.gov/pubmed/27096953
http://dx.doi.org/10.18632/oncotarget.8761