Integrin signaling via FAK-Src controls cytokinetic abscission by decelerating PLK1 degradation and subsequent recruitment of CEP55 at the midbody

Adhesion to extracellular matrix is required for cell cycle progression through the G1 phase and for the completion of cytokinesis in normal adherent cells. Cancer cells acquire the ability to proliferate anchorage-independently, a characteristic feature of malignantly transformed cells. However, th...

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Detalles Bibliográficos
Autores principales: Kamranvar, Siamak A., Gupta, Deepesh Kumar, Huang, Ying, Gupta, Rajesh Kumar, Johansson, Staffan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058720/
https://www.ncbi.nlm.nih.gov/pubmed/27127172
http://dx.doi.org/10.18632/oncotarget.9003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058720/
https://www.ncbi.nlm.nih.gov/pubmed/27127172
http://dx.doi.org/10.18632/oncotarget.9003

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